News, Seminars &
Isolation of antigen-specific, disulphide-rich knob domain peptides from bovine antibodies
As a novel alternative to established surface display or combinatorial chemistry approaches for the discovery of therapeutic peptides, we present a method for the isolation of small, cysteine-rich domains from bovine antibody ultralong complementarity-determining regions (CDRs).
A practical model of the diffusion of oil‐based fluid into polyethylene
It is possible to modify the properties of semicrystalline polymers using diffusion to introduce additional functionality.
CTI Autumn Newsletter
We open the Autumn Newsletter highlighting the strategies we have adopted to implement creative approaches to secure a larger portion of funding pools available post- COVID 19 era, as well as opportunistically moving into spaces created by this crisis.
MATWIN highlights six promising cancer research projects
Three projects chosen by MATWIN’s 13 partner laboratories, three by a panel of European investors
New tool identifies which cancer patients are most likely to benefit from immunotherapy
A new diagnostic tool that can predict whether a cancer patient would respond to immunotherapy treatment has been developed by scientists at the University of Bath.
High PD-1/PD-L1 checkpoint interaction infers tumor selection and therapeutic sensitivity to anti-PD-1/PD-L1 treatment
Many cancers are termed immunoevasive due to expression of immunomodulatory ligands. Programmed death ligand-1 (PD-L1) and cluster of differentiation 80/86 (CD80/86) interact with their receptors, programmed death receptor-1 (PD-1) and cytotoxic T-lymphocyte associated protein-4 (CTLA-4) respectively, on tumor-infiltrating leukocytes eliciting immunosuppression.
CTI publication outputs
CTI publications span a wide range of research areas. The figure below uses Scopus/SciVal’s broad subject categories to show the areas current CTI staff have published in since 2014.
Professor Guillaume Canaud, Necker Hospital, Paris
Targeted therapy in patients with PIK3CA-related overgrowth syndrome
Wednesday 25 November, 13:15See Details
Professor Paul Skipp, Professor of Proteomics at the University of Southampton and Director of the Centre for Proteomic Research
Precision Medicine: The Shape of Asthma
Thursday 3 December, 12:15See Details