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MATWIN highlights six promising cancer research projects
Three projects chosen by MATWIN’s 13 partner laboratories, three by a panel of European investors
New tool identifies which cancer patients are most likely to benefit from immunotherapy
A new diagnostic tool that can predict whether a cancer patient would respond to immunotherapy treatment has been developed by scientists at the University of Bath.
High PD-1/PD-L1 checkpoint interaction infers tumor selection and therapeutic sensitivity to anti-PD-1/PD-L1 treatment
Many cancers are termed immunoevasive due to expression of immunomodulatory ligands. Programmed death ligand-1 (PD-L1) and cluster of differentiation 80/86 (CD80/86) interact with their receptors, programmed death receptor-1 (PD-1) and cytotoxic T-lymphocyte associated protein-4 (CTLA-4) respectively, on tumor-infiltrating leukocytes eliciting immunosuppression.
TI Spring Newsletter
We open the Spring Newsletter with the regrettable news of Prof. Michael Wakelam passing away on the 31st March 2020. Michael was one of the key members of our Scientific Advisory Board as well as a great advocate for the University of Bath.
CTI publication outputs
CTI publications span a wide range of research areas. The figure below uses Scopus/SciVal’s broad subject categories to show the areas current CTI staff have published in since 2014.
The unprecedented membrane deformation of the human nuclear envelope, in a magnetic field, indicates formation of nuclear membrane invaginations
The unprecedented membrane deformation of the human nuclear envelope, in a magnetic field, indicates formation of nuclear membrane invaginations
A Complex Interplay of Anionic Phospholipid Binding Regulates 3′-Phosphoinositide-Dependent-Kinase-1 Homodimer Activation
3′-Phosphoinositide-dependent-Kinase-1 (PDK1) is a master regulator whereby its PI3-kinase-dependent dysregulation in human pathologies is well documented.
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